Reduced Angiopoietin-Like 4 Expression in Multiple Sclerosis Lesions Facilitates Lipid Uptake by Phagocytes via Modulation of Lipoprotein-Lipase Activity

Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system (CNS) characterized by the presence of focal demyelinated plaques. Sufficient clearance of myelin and cellular debris is one of the requirements for proper tissue repair and remyelination. The mechanisms underly...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Kamermans, Alwin, Rijnsburger, Merel, Chakraborty, Ananya, van der Pol, Susanne, de Vries, Helga E., van Horssen, Jack
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509157/
https://ncbi.nlm.nih.gov/pubmed/31130950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00950
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