The selective disruption of presynaptic JNK2/STX1a interaction reduces NMDA receptor-dependent glutamate release

The neuronal loss caused by excessive glutamate release, or ‘excitotoxicity’, leads to several pathological conditions, including cerebral ischemia, epilepsy, and neurodegenerative diseases. Over-stimulation of presynaptic N-methyl-D-aspartate (NMDA) receptors is known to trigger and support glutama...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Marcelli, Serena, Iannuzzi, Filomena, Ficulle, Elena, Mango, Dalila, Pieraccini, Stefano, Pellegrino, Sara, Corbo, Massimo, Sironi, Maurizio, Pittaluga, Anna, Nisticò, Robert, Feligioni, Marco
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509125/
https://ncbi.nlm.nih.gov/pubmed/31073146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43709-2
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы