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Changes in V-ATPase subunits of human urinary exosomes reflect the renal response to acute acid/alkali loading and the defects in distal renal tubular acidosis

In the kidney, final urinary acidification is achieved by V-ATPases expressed in type A intercalated cells. The B1 subunit of the V-ATPase is required for maximal urinary acidification, while the role of the homologous B2 subunit is less clear. Here we examined the effect of acute acid/alkali loadin...

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Vydáno v:Kidney Int
Hlavní autoři: Pathare, Ganesh, Dhayat, Nasser A., Mohebbi, Nilufar, Wagner, Carsten A., Bobulescu, Ion A., Moe, Orson W., Fuster, Daniel G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508879/
https://ncbi.nlm.nih.gov/pubmed/29310826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2017.10.018
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