Periosteal Mesenchymal Progenitor Dysfunction and Extraskeletally-Derived Fibrosis Contribute to Atrophic Fracture Nonunion

Atrophic nonunion represents an extremely challenging clinical dilemma for both physicians and fracture patients alike, but its underlying mechanisms are still largely unknown. Here, we established a mouse model that recapitulates clinical atrophic nonunion through the administration of focal radiat...

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Dades bibliogràfiques
Publicat a:J Bone Miner Res
Autors principals: Wang, Luqiang, Tower, Robert J, Chandra, Abhishek, Yao, Lutian, Tong, Wei, Xiong, Zekang, Tang, Kai, Zhang, Yejia, Liu, X Sherry, Boerckel, Joel D, Guo, Xiaodong, Ahn, Jaimo, Qin, Ling
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508876/
https://ncbi.nlm.nih.gov/pubmed/30602062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3626
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