Heme oxygenase-1—Dependent anti-inflammatory effects of atorvastatin in zymosan-injected subcutaneous air pouch in mice

Statins exert pleiotropic and beneficial anti-inflammatory and antioxidant effects. We have previously reported that macrophages treated with statins increased the expression of heme oxygenase-1 (HO-1), an inducible anti-inflammatory and cytoprotective stress protein, responsible for the degradation...

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Bibliographic Details
Published in:PLoS One
Main Authors: El-Achkar, Ghewa A., Mrad, May F., Mouawad, Charbel A., Badran, Bassam, Jaffa, Ayad A., Motterlini, Roberto, Hamade, Eva, Habib, Aida
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508873/
https://ncbi.nlm.nih.gov/pubmed/31071151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216405
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