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Molluscum contagiosum virus MC80 sabotages MHC-I antigen presentation by targeting tapasin for ER-associated degradation

The human specific poxvirus molluscum contagiosum virus (MCV) produces skin lesions that can persist with minimal inflammation, suggesting that the virus has developed robust immune evasion strategies. However, investigations into the underlying mechanisms of MCV pathogenesis have been hindered by t...

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Bibliografische gegevens
Gepubliceerd in:PLoS Pathog
Hoofdauteurs: Harvey, Ian B., Wang, Xiaoli, Fremont, Daved H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508746/
https://ncbi.nlm.nih.gov/pubmed/31034515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007711
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