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A46 THE IMPACT OF CYP2C19 POLYMORPHISM ON PROTON PUMP INHIBITORS DOSING: A RETROSPECTIVE ANALYSIS
BACKGROUND: Proton pump inhibitors (PPIs) are used in a wide spectrum of gastrointestinal disorders. They undergo significant metabolism by the main enzyme Cytochrome P450 2C19 (CYP2C19). Genetic variation in this enzyme influences the pharmacokinetics of all PPIs. Despite the different challenges w...
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| Publicado no: | J Can Assoc Gastroenterol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6508359/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy009.046 |
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