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A165 GENETIC DELETION OF HDAC1 AND HDAC2 DISRUPTS MURINE ENTEROID DEVELOPMENT AND METABOLIC PROGRAM

BACKGROUND: Histone deacetylases HDAC1 and HDAC2 are homologous enzymes removing acetyl groups from histones and non-histone proteins. This epigenetic mark regulates many biological processes including cell proliferation and differentiation. We have shown that HDAC1 and HDAC2 drive intestinal epithe...

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Detalhes bibliográficos
Publicado no:J Can Assoc Gastroenterol
Main Authors: Gonneaud, A, Turgeon, N, Jones, C, Couture, C, Boisvert, F, Boudreau, F, Asselin, C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508277/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy009.165
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