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A283 SECRETIONS OF INTESTINAL MICROBIOTA INCREASE THE EXCITABILITY OF VAGAL AFFERENT NEURONS VIA A PROTEASE ACTIVATED RECEPTOR 2 (PAR2)-DEPENDENT PATHWAY.

BACKGROUND: The intestinal microbiota has recently been shown to have pronounced effects on the central nervous system (CNS). However, it is presently unknown how intestinal microbes signal to the CNS. There are two afferent neural pathways linking the intestine and the CNS: the spinal afferent path...

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Detalles Bibliográficos
Publicado en:J Can Assoc Gastroenterol
Main Authors: Pradhananga, S, Lomax, A E, Allen-Vercoe, E, Petrof, E O
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508183/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy009.283
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