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Using a Hybrid Read-Across Method to Evaluate Chemical Toxicity Based on Chemical Structure and Biological Data

Read-across has become a primary approach to fill data gaps for chemical safety assessments. Chemical similarity based on structure, reactivity, and physic-chemical property information is a traditional approach applied for read-across toxicity studies. However, toxicity mechanisms are usually compl...

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Bibliographische Detailangaben
Veröffentlicht in:Ecotoxicol Environ Saf
Hauptverfasser: Guo, Yajie, Zhao, Linlin, Zhang, Xiaoyi, Zhu, Hao
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508079/
https://ncbi.nlm.nih.gov/pubmed/31004930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ecoenv.2019.04.019
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