The effects of BRCA1 expression on the chemosensitivity of gastric cancer cells to platinum agents

Breast cancer type 1 susceptibility protein (BRCA1) is a tumor suppressor gene that encodes a nuclear phosphoprotein, which is involved in homologous recombination to repair DNA double strand breaks and maintain genome stability. When BRCA1 is mutated or altered, DNA damage may not be effectively re...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: Kim, Geon, Kim, Jisu, Han, Su-Young, Hwang, In Gyu, Kim, Hee Sung, Min, Hyeyoung
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2019
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507359/
https://ncbi.nlm.nih.gov/pubmed/31186713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10169
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