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Serum pyruvate dehydrogenase kinase as a prognostic marker for cholangiocarcinoma

Pyruvate dehydrogenase kinase (PDK) is a Ser/Thr kinase that inactivates mitochondrial pyruvate dehydrogenase and serves a key role in aerobic glycolysis, which is a hallmark of cancer cells. The present study determined the PDK expression in cholangiocarcinoma (CCA) tissues and sera to evaluate the...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: Sanmai, Surangkana, Proungvitaya, Tanakorn, Limpaiboon, Temduang, Chua-On, Daraporn, Seubwai, Wunchana, Roytrakul, Sittiruk, Wongkham, Sopit, Wongkham, Chaisiri, Somintara, Ongart, Sangkhamanon, Sakkarn, Proungvitaya, Siriporn
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507336/
https://ncbi.nlm.nih.gov/pubmed/31186744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10185
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