Integrated omics-based pathway analyses uncover CYP epoxygenase-associated networks as theranostic targets for metastatic triple negative breast cancer

BACKGROUND: Current prognostic tools and targeted therapeutic approaches have limited value for metastatic triple negative breast cancer (TNBC). Building upon current knowledge, we hypothesized that epoxyeicosatrienoic acids (EETs) and related CYP450 epoxygenases may have differential roles in breas...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Apaya, Maria Karmella, Shiau, Jeng-Yuan, Liao, Guo-Shiou, Liang, Yu-Jen, Chen, Chia-Wei, Yang, Hsin-Chou, Chu, Chi-Hong, Yu, Jyh-Cherng, Shyur, Lie-Fen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507159/
https://ncbi.nlm.nih.gov/pubmed/31072371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1187-y
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