CRISPR Cpf1 proteins: structure, function and implications for genome editing

CRISPR and CRISPR-associated (Cas) protein, as components of microbial adaptive immune system, allows biologists to edit genomic DNA in a precise and specific way. CRISPR-Cas systems are classified into two main classes and six types. Cpf1 is a putative type V (class II) CRISPR effector, which can b...

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Bibliographic Details
Published in:Cell Biosci
Main Authors: Safari, Fatemeh, Zare, Khadijeh, Negahdaripour, Manica, Barekati-Mowahed, Mazyar, Ghasemi, Younes
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507119/
https://ncbi.nlm.nih.gov/pubmed/31086658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-019-0298-7
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