Changes in Both Neuron Intrinsic Properties and Neurotransmission Are Needed to Drive the Increase in GnRH Neuron Firing Rate during Estradiol-Positive Feedback

Central output of gonadotropin-releasing hormone (GnRH) neurons controls fertility and is sculpted by sex-steroid feedback. A switch of estradiol action from negative to positive feedback initiates a surge of GnRH release, culminating in ovulation. In ovariectomized mice bearing constant-release est...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Adams, Caroline, DeFazio, R. Anthony, Christian, Catherine A., Milescu, Lorin S., Schnell, Santiago, Moenter, Suzanne M.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2019
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507087/
https://ncbi.nlm.nih.gov/pubmed/30655354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2880-18.2019
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