Characterization of the molecular changes associated with the overexpression of a novel epithelial cadherin splice variant mRNA in a breast cancer model using proteomics and bioinformatics approaches: identification of changes in cell metabolism and an increased expression of lactate dehydrogenase B

BACKGROUND: Breast cancer (BC) is the most common female cancer and the leading cause of cancer death in women worldwide. Alterations in epithelial cadherin (E-cadherin) expression and functions are associated to BC, but the underlying molecular mechanisms have not been fully elucidated. We have pre...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Metab
Auteurs principaux: Rosso, Marina, Lapyckyj, Lara, Besso, María José, Monge, Marta, Reventós, Jaume, Canals, Francesc, Quevedo Cuenca, Jorge Oswaldo, Matos, María Laura, Vazquez-Levin, Mónica Hebe
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507066/
https://ncbi.nlm.nih.gov/pubmed/31086659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-019-0196-9
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