Low frequency of mismatch repair deficiency in gallbladder cancer

BACKGROUND: DNA mismatch repair (MMR) deficiency is a major pathway of genomic instability in cancer. It leads to the accumulation of numerous mutations predominantly at microsatellite sequences, a phenotype known as microsatellite instability (MSI). MSI tumors have a distinct clinical behavior and...

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Publicat a:Diagn Pathol
Autors principals: Goeppert, Benjamin, Roessler, Stephanie, Renner, Marcus, Loeffler, Moritz, Singer, Stephan, Rausch, Melina, Albrecht, Thomas, Mehrabi, Arianeb, Vogel, Monika Nadja, Pathil, Anita, Czink, Elena, Köhler, Bruno, Springfeld, Christoph, Rupp, Christian, Weiss, Karl Heinz, Schirmacher, Peter, von Knebel Doeberitz, Magnus, Kloor, Matthias
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506936/
https://ncbi.nlm.nih.gov/pubmed/31068195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-019-0813-5
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