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Lipid Bilayer Composition Influences the Activity of the Antimicrobial Peptide Dermcidin Channel

Antimicrobial peptides (AMPs) carry great potential as new antibiotics against “superbugs.” Dermcidin (DCD), a broad-spectrum AMP in human sweat, has been recently crystallized in its oligomeric state and showed channel-like properties. In this work, we performed multiscale molecular dynamics simula...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Song, Chen, de Groot, Bert L., Sansom, Mark S.P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506697/
https://ncbi.nlm.nih.gov/pubmed/31010668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.03.033
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