Targeting GATA transcription factors – a novel strategy for anti-aging interventions?

GATA transcription factors (TFs) are a conserved family of zinc-finger TFs that fulfill diverse functions across eukaryotes. Accumulating evidence suggests that GATA TFs also play a role in lifespan regulation. In a recent study, we have identified a natural compound, 4,4' dimethoxychalcone (DM...

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Udgivet i:Microb Cell
Main Authors: Zimmermann, Andreas, Kainz, Katharina, Hofer, Sebastian J., Bauer, Maria A., Schroeder, Sabrina, Dengjel, Jörn, Pietrocola, Federico, Kepp, Oliver, Ruckenstuhl, Christoph, Eisenberg, Tobias, Sigrist, Stephan J., Madeo, Frank, Kroemer, Guido, Carmona-Gutierrez, Didac
Format: Artigo
Sprog:Inglês
Udgivet: Shared Science Publishers OG 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506692/
https://ncbi.nlm.nih.gov/pubmed/31114793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2019.05.676
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