Novel aroylated phenylenediamine compounds enhance antimicrobial defense and maintain airway epithelial barrier integrity

Aroylated phenylenediamines (APDs) are novel inducers of innate immunity enhancing cathelicidin gene expression in human bronchial epithelial cell lines. Here we present two newly developed APDs and aimed at defining the response and signaling pathways for these compounds with reference to innate im...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Myszor, Iwona T., Parveen, Zahida, Ottosson, Håkan, Bergman, Peter, Agerberth, Birgitta, Strömberg, Roger, Gudmundsson, Gudmundur H.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506505/
https://ncbi.nlm.nih.gov/pubmed/31068616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43350-z
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