Insulin/IGF-1 Drives PERIOD Synthesis to Entrain Circadian Rhythms with Feeding Time

In mammals, endogenous circadian clocks sense and respond to daily feeding and lighting cues, adjusting internal ∼24 h rhythms to resonate with, and anticipate, external cycles of day and night. The mechanism underlying circadian entrainment to feeding time is critical for understanding why mistimed...

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Udgivet i:Cell
Main Authors: Crosby, Priya, Hamnett, Ryan, Putker, Marrit, Hoyle, Nathaniel P., Reed, Martin, Karam, Carolyn J., Maywood, Elizabeth S., Stangherlin, Alessandra, Chesham, Johanna E., Hayter, Edward A., Rosenbrier-Ribeiro, Lyn, Newham, Peter, Clevers, Hans, Bechtold, David A., O’Neill, John S.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506277/
https://ncbi.nlm.nih.gov/pubmed/31030999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.02.017
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