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A developmental program truncates long transcripts to temporally regulate cell signaling

Rapid mitotic divisions and a fixed transcription rate limit the maximal length of transcripts in early Drosophila embryos. Previous studies suggested that transcription of long genes is initiated but aborted, as early nuclear divisions have short interphases. Here, we identify long genes that are e...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Sandler, Jeremy E., Irizarry, Jihyun, Stepanik, Vincent, Dunipace, Leslie, Amrhein, Henry, Stathopoulos, Angelike
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506262/
https://ncbi.nlm.nih.gov/pubmed/30562515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.11.019
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