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Pathogenesis of Rickettsial Diseases: Pathogenic and Immune Mechanisms of an Endotheliotropic Infection

Obligately intracytosolic rickettsiae that cycle between arthropod and vertebrate hosts cause a spectrum of severity of human diseases by primarily targeting microvascular endothelial cells resulting in endothelial dysfunction. Endothelium and mononuclear phagocytes play important roles in intracell...

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Detalhes bibliográficos
Publicado no:Annu Rev Pathol
Main Authors: Sahni, Abha, Fang, Rong, Sahni, Sanjeev, Walker, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505701/
https://ncbi.nlm.nih.gov/pubmed/30148688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pathmechdis-012418-012800
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