Up-regulation of miR-155 contributes to TNF-mediated hepatocyte apoptosis in acute liver failure

BACKGROUND/AIMS: Acute liver failure (ALF) is due to severe immune response, resulting in massive apoptosis/necrosis of hepatocytes. The precise mechanism has not been explored yet. MATERIALS AND METHODS: The mouse with ALF model was induced by D-GalN/LPS; the hepatic miRNAs expression profile was e...

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Veröffentlicht in:Turk J Gastroenterol
Hauptverfasser: Zhang, Guoqiang, Yan, Chunyu, Chen, Dayang, Wu, Xiongbo, Zhang, Yunan, Zhan, Qiang, An, Fangmei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Turkish Society of Gastroenterology 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505647/
https://ncbi.nlm.nih.gov/pubmed/31061003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5152/tjg.2019.18159
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