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Human gut derived-organoids provide model to study gluten response and effects of microbiota-derived molecules in celiac disease

Celiac disease (CD) is an immune-mediated disorder triggered by gluten exposure. The contribution of the adaptive immune response to CD pathogenesis has been extensively studied, but the absence of valid experimental models has hampered our understanding of the early steps leading to loss of gluten...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Freire, Rachel, Ingano, Laura, Serena, Gloria, Cetinbas, Murat, Anselmo, Anthony, Sapone, Anna, Sadreyev, Ruslan I., Fasano, Alessio, Senger, Stefania
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505524/
https://ncbi.nlm.nih.gov/pubmed/31065051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43426-w
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