Extracellular Vesicles Released by Glioblastoma Cells Stimulate Normal Astrocytes to Acquire a Tumor-Supportive Phenotype Via p53 and MYC Signaling Pathways

The role of astrocytes is becoming increasingly important to understanding how glioblastoma (GBM) tumor cells diffusely invade the brain. Yet, little is known of the contribution of extracellular vesicle (EV) signaling in GBM/astrocyte interactions. We modeled GBM-EV signaling to normal astrocytes i...

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Pubblicato in:Mol Neurobiol
Autori principali: Hallal, S., Mallawaaratchy, D. M., Wei, H., Ebrahimkhani, S., Stringer, B. W., Day, B. W., Boyd, A. W., Guillemin, G. J., Buckland, M. E., Kaufman, Kimberley L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505517/
https://ncbi.nlm.nih.gov/pubmed/30353492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1385-1
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