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Cobalt Administration Causes Reduced Contractility with Parallel Increases in TRPC6 and TRPM7 Transporter Protein Expression in Adult Rat Hearts
Exposure to circulating cobalt (Co(2+)) in patients with metal-on-metal orthopaedic hip implants has been linked to cardiotoxicity but the underlying mechanism(s) remain undefined. The aim of the current study was to examine the effects of Co(2+) on the heart in vivo and specifically on cardiac fibr...
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| Publicado no: | Cardiovasc Toxicol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6505488/ https://ncbi.nlm.nih.gov/pubmed/30523498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12012-018-9498-3 |
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