A novel pancreatic cancer model originated from transformation of acinar cells in adult tree shrew, a primate-like animal

Pancreatic cancer is one of the most lethal common cancers. The cell of origin of pancreatic ductal adenocarcinoma (PDAC) has been controversial, and recent evidence suggested acinar cells as the most probable candidate. However, the genetic alterations driving the transformation of pancreatic acina...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Dis Model Mech
Prif Awduron: Tu, Qiu, Yang, Dong, Zhang, Xianning, Jia, Xintong, An, Sanqi, Yan, Lanzhen, Dai, Hongjuan, Ma, Yuhua, Tang, Chengwei, Tong, Weimin, Hou, Zongliu, Lv, Longbao, Tan, Jing, Zhao, Xudong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists Ltd 2019
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505477/
https://ncbi.nlm.nih.gov/pubmed/30910991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.038703
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