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Non-invasive detection of DNA methylation states in carcinoma and pluripotent stem cells using Raman microspectroscopy and imaging

DNA methylation plays a critical role in the regulation of gene expression. Global DNA methylation changes occur in carcinogenesis as well as early embryonic development. However, the current methods for studying global DNA methylation levels are invasive and require sample preparation. The present...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Daum, Ruben, Brauchle, Eva M., Berrio, Daniel Alejandro Carvajal, Jurkowski, Tomasz P., Schenke-Layland, Katja
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504883/
https://ncbi.nlm.nih.gov/pubmed/31065074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43520-z
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