Highly Multiplexed Fluorescence in Situ Hybridization for in Situ Genomics

The quantification of changes in gene copy number is critical to our understanding of tumor biology and for the clinical management of cancer patients. DNA fluorescence in situ hybridization is the gold standard method to detect copy number alterations, but it is limited by the number of genes one c...

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Veröffentlicht in:J Mol Diagn
Hauptverfasser: Onozato, Maristela L., Yapp, Clarence, Richardson, Douglas, Sundaresan, Tilak, Chahal, Varun, Lee, Jesse, Sullivan, James P., Madden, Marisa W., Shim, Hyo S., Liebers, Matthew, Ho, Quan, Maheswaran, Shyamala, Haber, Daniel A., Zheng, Zongli, Clancy, Brian, Elliott, Hunter L., Lennerz, Jochen K., Iafrate, A. John
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504678/
https://ncbi.nlm.nih.gov/pubmed/30862547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2019.01.010
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