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Aging leads to dysfunctional innate immune responses to TLR2 and TLR4 agonists.
BACKGROUND: Sepsis is more common in the elderly. TNFα is recognized as an important mediator in sepsis and Toll like receptors (TLRs) play an important role in initiating signaling cascades to produce TNFα. Little is known about how innate immunity is altered in healthy human aging that predisposes...
Enregistré dans:
| Publié dans: | Aging Clin Exp Res |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6504629/ https://ncbi.nlm.nih.gov/pubmed/30402800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40520-018-1064-0 |
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