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Clinical characterization of icotinib-induced chemoresistance in erlotinib-treated lung adenocarcinoma patient with EGFR mutations: A case report

RATIONALE: Mounting evidences reveal that mutation of epidermal growth factor receptor (EGFR) may induce the resistance of tyrosine kinase inhibitors (TKIs). TKI-resistant lung cancer cells are sensitive to inhibition of the EGFR pathway. This case report aimed to characterize the therapeutic benefi...

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Detalhes bibliográficos
Publicado no:Medicine (Baltimore)
Main Authors: Wu, Ka, Guo, Chao, Li, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504272/
https://ncbi.nlm.nih.gov/pubmed/31045832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000015489
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