DNA methylome of human neonatal umbilical cord: Enrichment of differentially methylated regions compared to umbilical cord blood DNA at transcription factor genes involved in body patterning and effects of maternal folate deficiency or children’s sex

The DOHaD (developmental origins of health and disease) hypothesis claims that fetal malnutrition or exposure to environmental pollutants may affect their lifelong health. Epigenetic changes may play significant roles in DOHaD; however, access to human fetuses for research has ethical and technical...

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Veröffentlicht in:PLoS One
Hauptverfasser: Sakurai, Kenichi, Shioda, Keiko, Eguchi, Akifumi, Watanabe, Masahiro, Miyaso, Hidenori, Mori, Chisato, Shioda, Toshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504184/
https://ncbi.nlm.nih.gov/pubmed/31063509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214307
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