Inhibition of Tumor Angiogenesis by a Synthetic Cell‐adhesive Polypeptide Containing the Arg‐Gly‐Asp (RGD) Sequence of Fibronectin, Poly(RGD)

We have investigated the anti‐angiogenic effect of a polymeric peptide based on the Arg‐Gly‐Asp (RGD) core sequence of fibronectin as a monomer unit, i.e., poly(RGD), in syngeneic mice and in vitro. Single intratumoral administration of poly(RGD) on day 0, 1 or 7 after tumor implantation achieved a...

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Publicado en:Jpn J Cancer Res
Autores principales: Saiki, Ikuo, Murata, Jun, Makabe, Takashi, Nishi, Norio, Tokura, Seiichi, Azuma, Ichiro
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 1990
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504046/
https://ncbi.nlm.nih.gov/pubmed/1698194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1990.tb02625.x
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