BET Bromodomain Inhibitors Suppress Inflammatory Activation of Gingival Fibroblasts and Epithelial Cells From Periodontitis Patients

BET bromodomain proteins are important epigenetic regulators of gene expression that bind acetylated histone tails and regulate the formation of acetylation-dependent chromatin complexes. BET inhibitors suppress inflammatory responses in multiple cell types and animal models, and protect against bon...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Maksylewicz, Anna, Bysiek, Agnieszka, Lagosz, Katarzyna B., Macina, Justyna M., Kantorowicz, Malgorzata, Bereta, Grzegorz, Sochalska, Maja, Gawron, Katarzyna, Chomyszyn-Gajewska, Maria, Potempa, Jan, Grabiec, Aleksander M.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503739/
https://ncbi.nlm.nih.gov/pubmed/31114581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00933
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