BET Bromodomain Inhibitors Suppress Inflammatory Activation of Gingival Fibroblasts and Epithelial Cells From Periodontitis Patients

BET bromodomain proteins are important epigenetic regulators of gene expression that bind acetylated histone tails and regulate the formation of acetylation-dependent chromatin complexes. BET inhibitors suppress inflammatory responses in multiple cell types and animal models, and protect against bon...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Maksylewicz, Anna, Bysiek, Agnieszka, Lagosz, Katarzyna B., Macina, Justyna M., Kantorowicz, Malgorzata, Bereta, Grzegorz, Sochalska, Maja, Gawron, Katarzyna, Chomyszyn-Gajewska, Maria, Potempa, Jan, Grabiec, Aleksander M.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503739/
https://ncbi.nlm.nih.gov/pubmed/31114581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00933
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