How to demix Alzheimer-type and PSP-type tau lesions out of their mixture -hybrid approach to dissect comorbidity-

Neurofibrillary tangles (NFTs), are shared between progressive supranuclear palsy (PSP) and Alzheimer disease (AD). Histological distinction of PSP and AD is possible based on the distribution of NFTs. However, neuropathologists may encounter diagnostic difficulty with comorbidity of PSP and AD. In...

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Veröffentlicht in:Acta Neuropathol Commun
Hauptverfasser: Ebashi, Momoko, Ito, Yoshinori, Uematsu, Miho, Nakamura, Ayako, Hirokawa, Katsuiku, Kamei, Satoshi, Uchihara, Toshiki
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503360/
https://ncbi.nlm.nih.gov/pubmed/31060611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0708-4
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