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Antitumor activity of larotrectinib in tumors harboring NTRK gene fusions: a short review on the current evidence

The development of deep-sequencing methods is now unveiling a new landscape of previously undetected gene fusion across different tumor types. Chromosomal translocation involving the NTRK gene family occur across a wide range of cancers in both children and adults. Preclinical studies have demonstra...

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Publicat a:Onco Targets Ther
Autors principals: Ricciuti, Biagio, Genova, Carlo, Crinò, Lucio, Libra, Massimo, Leonardi, Giulia Costanza
Format: Artigo
Idioma:Inglês
Publicat: Dove 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503327/
https://ncbi.nlm.nih.gov/pubmed/31118670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S177051
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