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Isobavachalcone isolated from Psoralea corylifolia inhibits cell proliferation and induces apoptosis via inhibiting the AKT/GSK-3β/β-catenin pathway in colorectal cancer cells

Background: Colorectal cancer (CRC) is a common form of cancer associated with a high mortality rate and poor prognosis. Given the limited efficacy of current therapies for CRC, interest in novel therapeutic agents isolated from natural sources has increased. We studied the anticancer properties of...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Li, Yanxi, Qin, Xiaoxue, Li, Penglei, Zhang, Hao, Lin, Tao, Miao, Ziwei, Ma, Siping
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503305/
https://ncbi.nlm.nih.gov/pubmed/31118579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S192681
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