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Sodium butyrate ameliorates insulin resistance and renal failure in CKD rats by modulating intestinal permeability and mucin expression

BACKGROUND: The associated increase in the lipopolysaccharide (LPS) levels and uremic toxins in chronic kidney disease (CKD) has shifted the way we focus on intestinal microbiota. This study shows that a disruption of the intestinal barrier in CKD promotes leakage of LPS from the gut, subsequently d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nephrol Dial Transplant
Hauptverfasser: Gonzalez, Austin, Krieg, Richard, Massey, Hugh D, Carl, Daniel, Ghosh, Shobha, Gehr, Todd W B, Ghosh, Siddhartha S
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503301/
https://ncbi.nlm.nih.gov/pubmed/30085297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfy238
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