Evaluating the Efficacies of Carbapenem/β-Lactamase Inhibitors Against Carbapenem-Resistant Gram-Negative Bacteria in vitro and in vivo

BACKGROUND: Carbapenem-resistant Gram-negative bacteria are a major clinical concern as they cause virtually untreatable infections since carbapenems are among the last-resort antimicrobial agents. β-Lactamases implicated in carbapenem resistance include KPC, NDM, and OXA-type carbapenemases. Antimi...

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Detalles Bibliográficos
Publicado en:Front Microbiol
Autores principales: El Hafi, Bassam, Rasheed, Sari S., Abou Fayad, Antoine G., Araj, George F., Matar, Ghassan M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503214/
https://ncbi.nlm.nih.gov/pubmed/31114565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.00933
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