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On the Complexity of Mechanisms and Consequences of Chromothripsis: An Update

In the present review, we focus on the phenomenon of chromothripsis, a new type of complex chromosomal rearrangements. We discuss the challenges of chromothripsis detection and its distinction from other chromoanagenesis events. Along with already known causes and mechanisms, we introduce aberrant e...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Koltsova, Alla S., Pendina, Anna A., Efimova, Olga A., Chiryaeva, Olga G., Kuznetzova, Tatyana V., Baranov, Vladislav S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503150/
https://ncbi.nlm.nih.gov/pubmed/31114609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00393
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