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Overcoming Resistance to Selective Serotonin Reuptake Inhibitors: Targeting Serotonin, Serotonin-1A Receptors and Adult Neuroplasticity

Major depressive disorder (MDD) is the most prevalent mental illness contributing to global disease burden. Selective serotonin (5-HT) reuptake inhibitors (SSRIs) are the first-line treatment for MDD, but are only fully effective in 30% of patients and require weeks before improvement may be seen. A...

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Bibliografiske detaljer
Udgivet i:Front Neurosci
Main Authors: Vahid-Ansari, Faranak, Zhang, Min, Zahrai, Amin, Albert, Paul R.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502905/
https://ncbi.nlm.nih.gov/pubmed/31114473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00404
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