Interleukin-7 Contributes to the Invasiveness of Prostate Cancer Cells by Promoting Epithelial–Mesenchymal Transition

Precise mechanisms underlying interleukin-7 (IL-7)-mediated tumor invasion remain unclear. Thus, we investigated the role of IL-7 in tumor invasiveness using metastatic prostate cancer PC-3 cell line derivatives, and assessed the potential of IL-7 as a clinical target using a Janus kinase (JAK) inhi...

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Publicat a:Sci Rep
Autors principals: Seol, Min A., Kim, Jin-Hee, Oh, Keunhee, Kim, Gwanghun, Seo, Myung Won, Shin, Young-Kyoung, Sim, Ji Hyun, Shin, Hyun Mu, Seo, Bo Yeon, Lee, Dong-Sup, Ku, Ja-Lok, Han, Ilkyu, Kang, Insoo, Park, Serk In, Kim, Hang-Rae
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502845/
https://ncbi.nlm.nih.gov/pubmed/31061414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43294-4
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