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PDA-TOLERATE Trial: An Exploratory Randomized Controlled Trial of Treatment of Moderate-to-Large Patent Ductus Arteriosus at 1 Week of Age

OBJECTIVE: To compare early routine pharmacologic treatment of moderate-to-large patent ductus arteriosus (PDA) at the end of week 1 with a conservative approach that requires prespecified respiratory and hemodynamic criteria before treatment can be given. STUDY DESIGN: A total of 202 neonates of &l...

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Detalhes bibliográficos
Publicado no:J Pediatr
Main Authors: Clyman, Ronald I., Liebowitz, Melissa, Kaempf, Joseph, Erdeve, Omer, Bulbul, Ali, Håkansson, Stellan, Lindqvist, Johanna, Farooqi, Aijaz, Katheria, Anup, Sauberan, Jason, Singh, Jaideep, Nelson, Kelly, Wickremasinghe, Andrea, Dong, Lawrence, Hassinger, Denise C., Aucott, Susan W., Hayashi, Madoka, Heuchan, Anne Marie, Carey, William A., Derrick, Matthew, Fernandez, Erika, Sankar, Meera, Leone, Tina, Perez, Jorge, Serize, Arturo
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502709/
https://ncbi.nlm.nih.gov/pubmed/30340932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpeds.2018.09.012
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