Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice

The transition from mitotic to meiotic cell cycles is essential for haploid gamete formation and fertility. Stimulated by retinoic acid gene 8 (Stra8) is an essential gatekeeper of meiotic initiation in vertebrates; yet, the molecular role of STRA8 remains principally unknown. Here we demonstrate th...

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Pubblicato in:PLoS Genet
Autori principali: Ferder, Ianina C., Fung, Leslie, Ohguchi, Yasuyo, Zhang, Xiaoyu, Lassen, Kara G., Capen, Diane, Brown, Dennis, Xavier, Ramnik J., Wang, Ning
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502318/
https://ncbi.nlm.nih.gov/pubmed/31059511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008084
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