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Breaking Amide C—N Bonds in an Undergraduate Organic Chemistry Laboratory

An undergraduate organic chemistry laboratory experiment involving the breakage of amide C—N bonds is reported. Whereas amides are typically considered stable species due to well-established resonance effects, this experiment allows students to cleave the amide C—N bond in a nickel-catalyzed esterif...

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Detalhes bibliográficos
Publicado no:J Chem Educ
Main Authors: Dander, Jacob E., Morrill, Lucas A., Nguyen, Melinda M., Chen, Shuming, Garg, Neil K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502258/
https://ncbi.nlm.nih.gov/pubmed/31073247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jchemed.8b00489
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