Botulinum toxin treatment of spasticity targeted to muscle endplates: an international, randomised, evaluator-blinded study comparing two different botulinum toxin injection strategies for the treatment of upper limb spasticity

OBJECTIVES: The therapeutic effects of botulinum neurotoxin (BoNT) are well documented in upper limb spasticity. However, several factors may influence treatment efficacy, including targeting of neuromuscular junctions (NMJs). We examined whether NMJ-targeted BoNT injections were non-inferior, in te...

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Publicado en:BMJ Open
Autores principales: Rekand, Tiina, Biering-Sörensen, Bo, He, Jun, Vilholm, Ole Jakob, Christensen, Peter Brøgger, Ulfarsson, Trandur, Belusa, Roger, Ström, Torbjörn, Myrenfors, Peter, Maisonobe, Pascal, Dalager, Torben
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Publishing Group 2019
Materias:
Rehabilitation Medicine
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502046/
https://ncbi.nlm.nih.gov/pubmed/31061021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2018-024340
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