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A complex containing lysine-acetylated actin inhibits the formin INF2
INF2 is a member of the formin family of actin assembly factors. Dominant mis-sense mutations in INF2 link to two diseases: focal segmental glomerulosclerosis (FSGS), a kidney disease; and Charcot-Marie-Tooth disease (CMTD), a neuropathy. All disease mutations map to the autoinhibitory Diaphanous In...
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| Pubblicato in: | Nat Cell Biol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6501848/ https://ncbi.nlm.nih.gov/pubmed/30962575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-019-0307-4 |
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