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HTiP: High-throughput immunomodulator phenotypic screening platform to reveal IAP antagonists as anti-cancer immune enhancers

Protein- and cell-based immunotherapeutic agents have revolutionized cancer treatment. However, small molecule immunomodulators with favorable pharmacological properties to reach intracellular targets remain to be developed. To explore the vast chemical space, a robust method that recapitulates the...

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Detalhes bibliográficos
Publicado no:Cell Chem Biol
Main Authors: Mo, Xiulei, Tang, Cong, Niu, Qiankun, Ma, Tingxuan, Du, Yuhong, Fu, Haian
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501824/
https://ncbi.nlm.nih.gov/pubmed/30639259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.11.011
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