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The Mobility of Histidine Side Chains Analyzed with (15)N NMR Relaxation and Cross-Correlation Data: Insight into Zinc-Finger – DNA Interactions

Due to chemical exchange, the mobility of histidine (His) side chains of proteins is typically difficult to analyze by NMR spectroscopy. Using an NMR approach that is uninfluenced by chemical exchange, we investigated internal motions of the His imidazole NH groups that directly interact with DNA ph...

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Veröffentlicht in:J Phys Chem B
Hauptverfasser: Kemme, Catherine A., Luu, Ross H., Chen, Chuanying, Pletka, Channing C., Pettitt, B. Montgomery, Iwahara, Junji
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501774/
https://ncbi.nlm.nih.gov/pubmed/30963768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b03132
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